This platform provides three analysis models including single, case-control and trio analysis.
1. Single Analysis
To create a single analysis, you can add minimum one sample and maximum ten samples per batch. You can select from the sample pool and assigns samples to the right side. Single analysis will do the annotation analysis for each single sample.
2. Case-Control Analysis
To create a case-control analysis, you can add minimum one sample to be assigned case group and mininum one sample to be assigned to control group. Case-control analysis will do analysis for all samples on each group. It is a type of observational study in which two existing groups differing in outcome are identified and compared on the basis of some supposed causal attribute. The analyzed results will show the variants which are only present in case group.
3. Trio Family Analysis
A family in which both parents are unaffected and one child is affected patient. First, you have to choose Inheritance Pattern (Model Selection Function) to be used in the analysis. We provide four disease models for trio-based analysis including:
3.1. Autosomal dominant
3.2. Autosomal recessive
3.3. X-linked dominant
3.4. X-linked recessive
To create a trio family analysis, you can add only one sample (male) to be assigned to Father, one sample (female) to be assigned to Mother, and one sample (male/female) need to be assigned to Son or Daughter.
The analyzed results will show the variants which are only present in child.